Oncology & Cancer

YBX1 as a key regulator of mitochondrial pyruvate uptake

Cancer metastasis is a crucial area in cancer research that directly affects patient survival and treatment outcomes. Cancer cells often undergo adaptive metabolic changes during metastasis from in situ to distant organs ...

Medical research

New test helps drug discoverers identify future cancer treatments

Researchers have developed an investigative procedure that makes the early stages of drug discovery more efficient. This test can help scientists identify new biologically active compounds that can be used to develop effective ...

Medical research

Researchers solve structure of immune-evading HIV protein complex

The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...

Immunology

How dendritic cells activate the immune system

The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...

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