Oncology & Cancer

Cancer drug design targeted by COSMIC's new 3-D system

COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, ...

Oncology & Cancer

Finding new cancer drugs in the neighborhood

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, ...

Neuroscience

Cause of cortical malformations targeted by researchers

Cortical malformations are a major cause of epileptic seizures and are a hallmark feature of many neurodevelopmental disorders. Expanding upon its recently-published model of cortical malformations, a Yale team lead by neuroscientist ...

Parkinson's & Movement disorders

Unravelling the biology of parkinsonism

Scientists have taken another step towards understanding the causes of parkinsonism by identifying what's happening at a cellular level to potentially help develop future treatments.

Medical research

A more powerful way to develop therapeutics?

A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics', a powerful class of medications that has revolutionized treatment of diseases like rheumatoid ...

Oncology & Cancer

Targeted missiles against aggressive cancer cells

Targeted missiles that can enter cancer cells and deliver lethal cell toxins without harming surrounding healthy tissue. This has been a long-standing vision in cancer research, but it has proved difficult to accomplish. ...

Neuroscience

Revealing the intra-cellular mechanism underlying ALS

A new study uncovering the mechanism behind amyotrophic lateral sclerosis (ALS or also Lou Gehrig's disease) has brought doctors a step closer to identifying drug targets for the malady. Tsukasa Uchida and collaborators at ...

page 18 from 29