Researchers have enhanced a new method for inhibiting the protein HSP72, known to be important in helping cancer cells survive and resist treatment, which will help scientists move closer to discovering a new cancer drug ...
Apr 6, 2020
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132
A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer. The study offers insights about how physicians ...
Feb 13, 2020
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58
In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that ...
Dec 18, 2019
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63
A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination. The research, which focuses ...
Oct 22, 2019
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148
What started as a hallway conversation between colleagues is now an "engine for the discovery of new therapeutic targets in cells" thanks to Medicine by Design, says Shana Kelley, a University Professor in the Leslie Dan ...
Sep 23, 2019
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53
A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments. ...
Jul 22, 2019
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29
In a breakthrough study published today in Nature Medicine, researchers at Joslin Diabetes Center have identified a group of 17 circulating inflammatory proteins that are consistently associated with the development and progression ...
Apr 22, 2019
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63
Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.
Apr 20, 2018
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260
Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers have discovered that accumulation of a type of lipid (fat), known as ceramides, plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition ...
Mar 6, 2018
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93
Scientists have created a map of all 1,578 licensed drugs and their mechanisms of action - as a means of identifying 'uncharted waters' in the search for future treatments.
Dec 5, 2016
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