Lidocaine—often used as a numbing agent for outpatient medical procedures—activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman ...
Nov 22, 2023
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Sensory neurons pick up information from our senses and relay it to the rest of the nervous system. But this is not their only mission. In a new study published in the journal Current Biology, Claire Wyart at the Paris Brain ...
Feb 15, 2023
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Sour is the taste of summer, a taste that evokes lemonade stands and vine-ripe tomatoes. Among the five basic tastes—the others being bitter, sweet, salty and umami—it is arguably the most subtle. In small amounts, it ...
Sep 19, 2019
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By tangling up bitter- and sweet-sensing cells on the tongues of mice, researchers have teased apart how the taste system wires itself. The results, from Howard Hughes Medical Institute (HHMI) Investigator Charles Zuker at ...
Aug 9, 2017
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Public health efforts to reduce dietary sodium intake have been hindered by an incomplete understanding of the complex process by which humans and other mammals detect salty taste.
Feb 11, 2016
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According to new research from the Monell Center, receptors for stress-activated hormones have been localized in oral taste cells responsible for detection of sweet, umami, and bitter. The findings suggest that these hormones, ...
Jun 3, 2014
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Fruit flies have a lot to teach us about the complexity of food. Like these tiny little creatures, most animals are attracted to sugar but are deterred from eating it when bitter compounds are added.
Aug 21, 2013
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Scientists from the Monell Center report the surprising finding that two proteins involved in oral taste detection also play a crucial role in sperm development.
Jul 1, 2013
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Scientists at the Monell Center have identified the location and certain genetic characteristics of taste stem cells on the tongue. The findings will facilitate techniques to grow and manipulate new functional taste cells ...
Feb 4, 2013
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A new study from a team of researchers at the Perelman School of Medicine at the University of Pennsylvania, the Monell Chemical Senses Center, and the Philadelphia VA Medical Center, reveals that a person's ability to taste ...
Oct 8, 2012
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