Medical research

Alzheimer's disease protein links plaques to cell death in mice

A new protein involved in Alzheimer's disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). CAPON may facilitate the connection between the two most well-known AD culprits, amyloid plaques ...

Psychology & Psychiatry

Gene discovered associated with Tau pathology

Investigators at Rush University Medical Center and the Brigham and Women's Hospital in Boston reported the discovery of a new gene that is associated with susceptibility to a common form of brain pathology called Tau that ...

Neuroscience

Brain network decay detected in early Alzheimer's

In patients with early Alzheimer's disease, disruptions in brain networks emerge about the same time as chemical markers of the disease appear in the spinal fluid, researchers at Washington University School of Medicine in ...

Alzheimer's disease & dementia

Mouse study explores Alzheimer's link to the X chromosome

Evidence in mouse and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report October 4 in the journal Cell that ...

Neuroscience

Clinical decline in Alzheimer's requires plaque and proteins

According to a new study, the neuron-killing pathology of Alzheimer's disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of ...

Neuroscience

Super-agers show resistance to tau and amyloid accumulation

Super-agers, or individuals whose cognitive skills are above the norm even at an advanced age, have been found to have increased resistance to tau and amyloid proteins, according to research presented at the Society of Nuclear ...

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