A study from Massachusetts General Hospital (MGH) investigators sheds new light on how the hallmarks of Alzheimer's disease—amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau—produce ...
Dec 19, 2018
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An international team led by Case Western Reserve University's School of Medicine has made a significant breakthrough in understanding why Alzheimer's disease progresses so rapidly in some people that they die within three ...
Jan 5, 2022
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Abnormal accumulation of misfolded tau protein in filaments characterizes numerous neurodegenerative diseases—collectively called tauopathies for this very reason. A long-standing collaboration between Michel Goedert's ...
Sep 30, 2021
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A new study led by investigators at Massachusetts General Hospital (MGH), in collaboration with the University of Antioquia, Schepens Eye Research Institute of Mass. Eye and Ear, and Banner Alzheimer's Institute, provides ...
Nov 4, 2019
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A world-first trial at UCL and UCLH has found a new genetic therapy for Alzheimer's disease that is able to safely and successfully lower levels of the harmful tau protein known to cause the disease.
Apr 25, 2023
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Alzheimer's disease is a brain disorder that causes neurons to die, slowly destroying memory and thinking skills. It's the most common type of dementia, impacting an estimated 50 million people worldwide, and is a particularly ...
Jun 22, 2022
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A genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins associated with Alzheimer's disease, amyloid β and tau, according to a study published in ...
Sep 16, 2020
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Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.
Aug 27, 2021
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A global team of researchers has discovered a new biomarker that could be used to detect Alzheimer's disease decades before symptoms emerge.
Mar 20, 2020
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Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological ...
Jan 15, 2013
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