Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold. Prior studies have considered this excessive daytime napping ...
Aug 12, 2019
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Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons. And similar to other quality control processes, the VPS35 system goes a long way toward protecting ...
Jul 9, 2019
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A study by investigators at Massachusetts General Hospital (MGH) finds evidence that spread through the brain of the Alzheimer's-disease-associated protein tau is facilitated by factors within the aging brain itself and not ...
Jun 26, 2019
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Two proteins central to the pathology of Alzheimer's disease act as prions—misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape—according to new ...
May 1, 2019
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Researchers at the MRC Laboratory of Molecular Biology (LMB) have revealed the atomic structures of the abnormal tau filaments associated with chronic traumatic encephalopathy (CTE), a head injury-associated neurodegenerative ...
Mar 21, 2019
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The accumulation of amyloid beta (Aβ) plaques and tangles of a protein called tau in the brain are hallmarks of Alzheimer's disease (AD). Much effort has focused on the former, with many attempts made to prevent, slow or ...
Jan 25, 2019
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A study from Massachusetts General Hospital (MGH) investigators sheds new light on how the hallmarks of Alzheimer's disease—amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau—produce ...
Dec 19, 2018
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Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University ...
Dec 17, 2018
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Scientists who recently identified the molecular start of Alzheimer's disease have used that finding to determine that it should be possible to forecast which type of dementia will develop over time—a form of personalized ...
Dec 11, 2018
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Zombie cells are the ones that can't die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, ...
Sep 19, 2018
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