A multi-institutional study led by investigators at Massachusetts General Hospital (MGH) and Johns Hopkins School of Medicine has found how the abnormal form of tau that accumulates in the neurofibrillary tangles that characterize ...
Sep 5, 2018
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195
A type of cellular stress known to be involved in cancer and aging has now been implicated, for the first time, in Alzheimer's disease. UT Health San Antonio faculty researchers reported the discovery Monday [August 20, 2018] ...
Aug 22, 2018
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586
A landmark study published in the journal Brain from the Mario Negri Institute for Pharmacological Research of Milan and the University of Glasgow provides first evidence that just a single traumatic brain injury can generate ...
Aug 1, 2018
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89
Scientists have discovered a "Big Bang" of Alzheimer's disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.
Jul 10, 2018
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2039
A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells. The scientists' new research, published this week ...
Jun 28, 2018
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109
New evidence suggests a mechanism by which progressive accumulation of Tau protein in brain cells may lead to Alzheimer's disease. Scientists studied more than 600 human brains and fruit fly models of Alzheimer's disease ...
Jun 5, 2018
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85
Alzheimer's disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau. Not only are these "tau aggregates" toxic for the cells that harbor them, but they also invade ...
May 2, 2018
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135
The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) - the muscle-crippling neurodegenerative disease that afflicted the late astrophysicist Stephen Hawking and cut short the career of iconic ...
Apr 9, 2018
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173
Alzheimer's disease is most often characterized by two different pathologies in the brain: plaque deposits of a protein called beta-amyloid and tangles of another protein called tau. A paper appearing March 21 in the journal ...
Mar 21, 2018
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96
Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer's disease - and hence that blocking its spread ...
Jan 5, 2018
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