By injecting human Alzheimer's disease brain extracts of pathological tau protein (from postmortem donated tissue) into mice with different amounts of amyloid-β (Aβ) plaques in their brains, researchers from the Perelman ...
Dec 4, 2017
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The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems ...
Nov 22, 2017
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In a new study, researchers from Boston University School of Medicine (BUSM) describe a unique model for the biology of Alzheimer's disease (AD) which may lead to an entirely novel approach for treating the disease. The findings ...
Nov 20, 2017
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Treatment with a neuroprotective compound that saves brain cells from dying also prevents the development of depression-like behavior and the later onset of memory and learning problems in a rat model of Alzheimer's disease. ...
Nov 6, 2017
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Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially raise a person's risk of the ...
Oct 9, 2017
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Nearly a quarter century ago, a genetic variant known as ApoE4 was identified as a major risk factor for Alzheimer's disease—one that increases a person's chances of developing the neurodegenerative disease by up to 12 ...
Sep 20, 2017
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Researchers at the MRC Laboratory of Molecular Biology (LMB) have, for the first time, revealed the atomic structures of one of the two types of the abnormal filaments which lead to Alzheimer's disease. Understanding the ...
Jul 6, 2017
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69
Japanese scientists have developed a method to isolate and identify active compounds in plant medicines, which accurately accounts for drug behavior in the body. Using the technique, they have identified several active compounds ...
Jun 20, 2017
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Damaging tangles of the protein tau dot the brains of people with Alzheimer's and many other neurodegenerative diseases, including chronic traumatic encephalopathy, which plagues professional boxers and football players. ...
Apr 19, 2017
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136
Unique graphic characters called Greebles may prove to be valuable tools in detecting signs of Alzheimer's disease decades before symptoms become apparent.
Apr 11, 2017
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