Medical research

Research resolves contradiction over protein's role at telomeres

Mice and humans share a lot more than immediately meets the eye, and their commonalities include their telomeres, protective ends on chromosomes. But in recent years, the role of one particular protein at telomeres has puzzled ...

Oncology & Cancer

How the ends of chromosomes are maintained for cancer cell immortality

Maintaining the ends of chromosomes, called telomeres, is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer. "Telomeres are much like the plastic cap on the ends of shoelaces—they ...

Genetics

Researchers discover a new gene involved in obesity

The discovery of an unexpected function for a gene that was associated to another process in the organism might be a solution in search of a problem, a clue to unsuspected connections. That is what has happened with RAP1, ...

Cardiology

Cellular aging increases risk of heart attack and early death

Every cell in the body has chromosomes with so-called telomeres, which are shortened over time and also through lifestyle choices such as smoking and obesity. Researchers have long speculated that the shortening of telomeres ...

Medical research

Alternate ending -- living on without telomerase

Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes.

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