Medical research

Mouse model aids study of immunomodulation

Because mice do not respond to immunomodulatory drugs (IMiDs), preclinical therapeutic and safety studies of the effects of IMiDs have not been possible in existing types of mice. This has led to an inability to accurately ...

Diseases, Conditions, Syndromes

Stellate ganglion block beneficial in postherpetic neuralgia

(HealthDay)—The therapeutic benefit of stellate ganglion block for debilitating photophobia secondary to trigeminal postherpetic neuralgia has been described in a case report published online July 5 in Pain Practice.

Psychology & Psychiatry

Discovering why antidepressants don't work well for kids

Depression is a major health problem for which most patients are not effectively treated. In particular, depression is an increasing problem in children and teenagers. The most commonly prescribed antidepressants are selective ...

Other

BMJ editorial: India's research participant protection policy

In an editorial published online today in BMJ, Johns Hopkins bioethicist Jeremy Sugarman and other experts warn that action is urgently needed to deal with possible unintended consequences of India's new policy protecting ...

Neuroscience

Compound enhances SSRI antidepressant's effects in mice

A synthetic compound is able to turn off "secondary" vacuum cleaners in the brain that take up serotonin, resulting in the "happy" chemical being more plentiful, scientists from the School of Medicine at The University of ...

Genetics

Candidate drug provides benefit in SMA animal models

In a new publication that appears in Human Molecular Genetics, the laboratory of Christine DiDonato, PhD reports on their pharmacological characterization of the drug RG3039, demonstrating that it can extend survival and ...

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