Alzheimer's disease & dementia

New compound shows promise in treatment of Alzheimer's

Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer's and even restores memories in mice, they report Jan. 2 in the journal Cell Reports.

Medical research

T-cell biofactories find, fight disease in one fell swoop

NIBIB-funded researchers have transformed T cells into drug factories engineered to find cells carrying specific diseases in the body—and then produce therapeutic proteins localized to the diseased cells.

Parkinson's & Movement disorders

Toward a better understanding of Parkinson's disease

A new study, published today in Nature Structural and Molecular Biology, moves researchers closer to understanding one of the crucial proteins involved in Parkinson's disease.

Cardiology

Controlling ceramides could help treat heart disease

Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers have discovered that accumulation of a type of lipid (fat), known as ceramides, plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition ...

Medical research

Reversing severe bone loss

A possible first-line treatment for a rare bone loss disease has been identified by a research team led by Tohoku University in Japan. The research findings, published in the journal Molecular Cell, could also provide insight ...

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