Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers have discovered that accumulation of a type of lipid (fat), known as ceramides, plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition ...
Mar 6, 2018
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A possible first-line treatment for a rare bone loss disease has been identified by a research team led by Tohoku University in Japan. The research findings, published in the journal Molecular Cell, could also provide insight ...
Feb 7, 2018
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Affecting as many as 650 million people worldwide, obesity has become one of the most serious global health issues. Among its detrimental effects, it increases the risk of developing metabolic conditions, and primarily type ...
Nov 28, 2017
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(HealthDay)—Metformin has therapeutic potential as a post-ischemic conditioning agent, according to a study published online June 23 in Cardiovascular Therapeutics.
Jun 29, 2017
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A naturally occurring human enzyme -called cyclophilin 40 or CyP40- can unravel protein aggregates that contribute to both Alzheimer's disease and Parkinson's disease, according to a study publishing June 27 in the open access ...
Jun 27, 2017
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COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, ...
May 10, 2017
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According to the Centers for Disease Control and Prevention, approximately 735,000 Americans experience a heart attack each year. Opening a blocked coronary artery to restore blood flow to the heart prevents sudden cardiac ...
Mar 23, 2017
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Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are ...
Mar 2, 2017
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The long-term safety of gene transfer to treat neovascular age-related macular degeneration (NVAMD), and the production of two therapeutic proteins encoded by those genes for at least 2.5 years in the eyes of patients with ...
Oct 20, 2016
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Researchers at University of California San Diego School of Medicine have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated ...
Oct 12, 2016
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