Results from the NRG Oncology phase I clinical trial NRG-GOG 9929 show that using the immunotherapy drug ipilimumab after chemoradiotherapy (CRT) is tolerated in the curative treatment of women with lymph node-positive cervical ...
Dec 3, 2019
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A novel method uses subcellular fractionation to quantify label-free antisense oligonucleotides (AONs)- designed to silence targeted genes—that have crossed into the nucleus of a cell, where they can exert their effects. ...
Nov 14, 2019
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When antigens such as a virus or bacteria invade our body, the immune system springs into action: it creates antibodies that stick to the antigens so that they can identify and destroy the intruders. Did you know that these ...
Oct 15, 2019
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Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread. There is an urgent need to evaluate more therapeutic targets. The chemotherapeutic agent ...
Aug 19, 2019
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Cancer researchers at the University of Virginia School of Medicine have identified a key to controlling the growth and progression of prostate cancer, the second most common cancer in men. The researchers have dubbed this ...
Jul 29, 2019
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Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed an experimental therapeutic to block ...
Jul 23, 2019
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A reconfigurable "body-on-a-chip" model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver. These findings, published ...
Jun 19, 2019
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Multiple sclerosis is an autoimmune disease that damages the insulating sheaths of nerve cells of the central nervous system. People with the disease can lose vision, suffer weak limbs, show degenerative symptoms and exhibit ...
May 28, 2019
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Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules. Researchers at Winship Cancer Institute of Emory University ...
Mar 12, 2019
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An international team of researchers has identified a novel route that regulates the signaling pathways induced by extracellular matrix (ECM). This may serve as a new diagnostic marker and therapeutic target in the fight ...
Jan 21, 2019
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