Scientists at St. Jude Children's Research Hospital, alongside collaborators around the world, have created a comprehensive reference of functional variants in an important drug-metabolizing enzyme called NUDT15. This thorough ...
Feb 25, 2020
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(HealthDay)—Elderly patients with inflammatory bowel disease (IBD) are at higher risk for adverse events (AEs) related to the use of thiopurines, according to a study published in the October issue of Alimentary Pharmacology ...
Oct 1, 2019
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Researchers from Japan's Tohoku University and colleagues have found that a simple DNA test can predict if East Asian patients are likely to have bad reactions to thiopurine medications.
Jul 2, 2018
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(HealthDay)—For patients with inflammatory bowel disease (IBD), the risk of lymphoma is increased with use of thiopurine monotherapy, anti-tumor necrosis factor (TNF) monotherapy, and combination therapy, according to a ...
Nov 8, 2017
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