Cardiology

How Gata4 helps mend a broken heart

During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead it replaces dead tissue with scars made of cells called fibroblasts ...

Diseases, Conditions, Syndromes

Drug to tackle lung scarring shows promise

People with a lung scarring condition that leaves them fighting for breath could be helped by a new medication, research suggests.

Diseases, Conditions, Syndromes

A promising target for kidney fibrosis

When the kidneys - vital organs for filtering the body's entire blood supply - become injured, it can set in motion an unfortunate chain of events that leads to a decline in health. Sometimes, in response to chronic injury, ...

Diseases, Conditions, Syndromes

Study finds key regulator in pulmonary fibrosis

A Yale-led research team has identified an important enzyme that could lead to new therapies for a chronic fatal lung disease that affects hundreds of thousands in the United States each year.

Diseases, Conditions, Syndromes

Study finds shared network of genes in COPD and pulmonary fibrosis

Research on chronic lung diseases has primarily focused on studying conditions, such as emphysema or lung fibrosis, in isolation. In a new study, Yale scientists identified a common genetic network for two chronic lung diseases ...

Arthritis & Rheumatism

New way of classifying scleroderma

A new way of classifying scleroderma will greatly help the diagnosis and stratification of the debilitating medical condition, as well as assist in researching other autoimmune diseases.

Diseases, Conditions, Syndromes

Researchers illuminate key role of NOX proteins in liver disease

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th ...

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