During a stroke or organ transplant, patients can suffer an injury due to lack of blood supply to vital organs. The injury—known as ischemia reperfusion—can cause damage to tissues. But a new Yale-led study has identified ...
Jun 21, 2017
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Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers ...
Oct 26, 2020
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Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research ...
Mar 30, 2021
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Children with liver transplants must take immunosuppressant medications for life. To maintain tolerance of the transplanted liver, doctors treat transplant rejection and conduct ongoing maintenance immunosuppression by increasing ...
Apr 17, 2024
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Gravity can be a real downer when you are trying to grow organs.
Jul 8, 2020
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Researchers at the University of Colorado Anschutz Medical Campus have found that fat cells produced by stem cells from the bone marrow may be linked to chronic illnesses like diabetes, cardiovascular disease, kidney disease ...
Nov 24, 2015
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With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step ...
Oct 18, 2012
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With the only cure for liver cancer often being a transplantation, scientists are honing the selection of patients for this life-saving surgery and growing replacement livers in a lab.
Jan 10, 2023
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The microgravity environment of the International Space Station impacts nearly every system within the human body. Researchers are studying the effects to the eyes, heart, muscles, and bones, but an area that hasn't received ...
Oct 23, 2017
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Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk, a study suggests. The results also suggest that low levels of this protein, ...
Aug 22, 2013
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