Oncology & Cancer

Cellular pumps protect the gut from toxins

The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...

Diabetes

Toxic proteins and type 2 diabetes

Nearly a half-billion people worldwide live with type 2 diabetes. Yet despite the disease's sizeable and increasing impact, its precise causes remain murky. Current scientific thinking points to two key processes: insulin ...

Genetics

Potential drug targets for ALS revealed in study using CRISPR

In a new application of gene-editing technology, researchers at the Stanford University School of Medicine have gleaned insights into the genetic underpinnings of amyotrophic lateral sclerosis, a neurodegenerative disease ...

Neuroscience

Scientists move closer to treatment for Huntington's disease

A new variant of the gene-editing CRISPR/Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in ...

Parkinson's & Movement disorders

Progression of Parkinson's disease follows brain connectivity

A study by a group of researchers including those from The Montreal Neurological Institute and Hospital of McGill University has tested the theory that brain degeneration in Parkinson's disease (PD) originates in subcortical ...

Parkinson's & Movement disorders

Tug of war between Parkinson's protein and growth factor

Alpha-synuclein, a sticky and sometimes toxic protein involved in Parkinson's disease (PD), blocks signals from an important brain growth factor, Emory researchers have discovered.

Alzheimer's disease & dementia

Study offers new insight into how Alzheimer's disease begins

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. The researchers found a relationship between inflammation, a toxic protein ...

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