Oncology & Cancer

Discovery suggests new way to target mantle cell lymphoma

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma ...

Oncology & Cancer

Researchers discover master regulator in cancer metastasis

In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers ...

Oncology & Cancer

Scientists uncover novel mechanism of glioblastoma development

Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally ...

Oncology & Cancer

RNA promotes metastasis in lung cancer

The vast majority – approximately 80 percent – of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied ...

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