Medical research
Study finds age-associated gene expression changes in mouse sweat glands
A new research paper published in Aging is titled "Characterization of age-associated gene expression changes in mouse sweat glands."
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News tagged with transcription
Genetics
Machine learning sheds light on gene transcription
A team led by researchers at UT Southwestern Medical Center has developed deep learning models to identify a simple set of rules that govern the activity of promoters—regions of DNA that initiate the process by which genes ...
May 14, 2024
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Genetics
Study links organization of neurotypical brains to genes involved in autism and schizophrenia
The organization of the human brain develops over time, following the coordinated expression of thousands of genes. Linking the development of healthy brain organization to genes involved in mental health conditions such ...
Oncology & Cancer
Drug targeting RNA modifications shows promise for treating neuroblastoma
Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain. While increasingly intensive treatments have improved the survival of patients with high-risk neuroblastoma, currently ...
May 3, 2024
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Oncology & Cancer
Unraveling the roles of non-coding DNA explains childhood cancer's resistance to chemotherapy
St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL). The results guided ...
May 1, 2024
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Immunology
Gene expression analyses identify potential drivers of chronic allergic inflammation
Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, ...
Apr 30, 2024
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Oncology & Cancer
Unlocking the immune system: cGAS-STING pathway offers new hope for cancer treatment
Cancer immunotherapy, which leverages the body's immune system to target tumors, has emerged as a pivotal strategy in oncology. This paradigm shift from conventional treatments offers a more precise method to neutralize cancer ...
Apr 30, 2024
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Oncology & Cancer
Liver cancer: Molecular signaling pathway of tumor development decoded
As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain limited, the incidence is ...
Apr 23, 2024
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Genetics
Mouse study uncovers how altered gene expression can induce autism
Autism spectrum disorder (ASD) encompasses neurodevelopmental conditions where patients display repetitive behavior and impaired sociality. Genetic factors have been shown to influence the development of ASD. Additionally, ...
Apr 9, 2024
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Genetics
New atlas of mRNA variants captures inner workings of the brain
Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, ...
Apr 9, 2024
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