Immunology
How an immune system regulator shifts the balance of immune cells
Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.
Feb 4, 2020
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Page 22 - News tagged with transcription
Diseases, Conditions, Syndromes
Liver fibrosis 'off switch' discovered in mice
Chronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding this process, known as liver fibrosis, could help researchers develop new ways to prevent or ...
Jan 23, 2020
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Medical research
Editing RNA delivers precision strike on triple-negative breast cancer
The move toward targeted anti-cancer treatments has produced better outcomes with fewer side-effects for many breast cancer patients. But so far, advances in precision medicine haven't reached people diagnosed with so-called ...
Jan 21, 2020
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Oncology & Cancer
Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone
The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds. The bush also provides the chemical bouvardin, which the lab of University of ...
Jan 8, 2020
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Medications
New compounds block master regulator of cancer growth, metastasis
Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and ...
Jan 7, 2020
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Oncology & Cancer
Immune cell discovery opens door to new powerful cancer therapies
Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer.
Jan 7, 2020
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Neuroscience
New approach for studying experience-driven activity of transcription factors in vivo
Brains are highly adaptable. Neuronal connections are constantly changing, molded by what people experience in their daily lives. New memories, information learned, and new skills spark this dynamic process, causing lasting ...
Dec 27, 2019
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Oncology & Cancer
Possible strategy for cancer treatment found in nuclear transport proteins
Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors. Now researchers at Kanazawa University and collaborating institutions ...
Dec 17, 2019
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Oncology & Cancer
Math equation predicts and detects liver cancer
By combining RNA sequencing, bioinformatics and mathematical modeling, University of California San Diego School of Medicine and Moores Cancer Center researchers identified a sudden transcriptomic switch that turns healthy ...
Dec 17, 2019
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Cardiology
Developing next-generation biologic pacemakers
University of Houston associate professor of pharmacology Bradley McConnell is helping usher in a new age of cardiac pacemakers by using stem cells found in fat, converting them to heart cells, and reprogramming those to ...
Dec 16, 2019
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