Immunology
New research targets immune system vulnerabilities
In the battle against infections and diseases, from AIDS to cancer to diabetes, T-cells are the human body's first line of defense.
Aug 5, 2016
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Page 35 - News tagged with transcription
Psychology & Psychiatry
Protein found to regulate cocaine craving after withdrawal
Neuroscientists know that cocaine addiction and withdrawal rewire the brain. But figuring out how to disrupt those changes to treat addiction requires an extremely detailed understanding of how those changes occur.
Aug 2, 2016
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Oncology & Cancer
Krüppel-like factor 12 promotes colorectal cancer via early growth response protein 1
Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, ...
Jul 29, 2016
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Neuroscience
Researchers identify genome-modifying enzyme linked to Rett Syndrome
People with Rett Syndrome, a rare and debilitating neurodevelopmental disorder, exhibit many autism-like traits. Now researchers at MIT have identified a protein that plays an important role in the disorder. The researchers ...
Jul 25, 2016
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Immunology
Proteins team up to turn on T cells
The fates of various cells in our bodies—whether they become skin or another type of tissue, for example—are controlled by genetic switches. In a new study, Caltech scientists investigate the switch for T cells, which ...
Jul 15, 2016
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Genetics
Tendon, heal thyself: Study reveals gene crucial in keeping tendons healthy
With the Rio Olympics just weeks away, many are wondering how Jamaican sprinter Usain Bolt will perform. Bolt is the fastest runner ever timed, but he's also been nursing a tendon injury—the kind of injury that can take ...
Jul 13, 2016
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Oncology & Cancer
New mechanism activates the immune system against tumour cells
The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells. Veronika ...
Jun 17, 2016
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Medical research
Clarifying the role of CHOP/GADD153 in cell death
The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the May 2016 issue of Nature Communications demonstrate that CHOP/GADD153-dependent apoptosis reflects expression ...
May 13, 2016
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Parkinson's & Movement disorders
Identifying a genetic mutation behind sporadic Parkinson's disease
Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies (GWAS) can contribute to sporadic Parkinson's disease (PD). The approach could ...
Apr 20, 2016
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Oncology & Cancer
Breast cancer stem cells radicalize normal neighbors for purpose of metastasis
A University of Colorado Cancer Center study presented at the American Association for Cancer Research Annual Meeting 2016 shows that stem-like breast cancer cells secrete molecules that allow neighboring, otherwise anchored ...
Apr 18, 2016
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