Medical research

New approach to protecting prion protein from altering shape

A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for ...

Oncology & Cancer

The novel mechanisms for inflammation and cancer induced by HTLV-1

A research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes inflammation and oncogenesis. The action of the viral gene HTLV-1 bZIP factor (HBZ) ...

Alzheimer's disease & dementia

Loss of memory in Alzheimer's mice models reversed through gene therapy

Alzheimer's disease is the leading cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge about the cellular mechanisms ...

Cardiology

Obesity negates beneficial drug effects

Blocking CETP—a protein that shuttles cholesterol and triglycerides between lipoproteins such as HDL and LDL—has been shown to improve levels of the "good" cholesterol HDL. Outcomes from clinical trials of CETP inhibitors, ...

Diabetes

A further step towards preventing diabetes

Having identified the important role in controlling insulin secretion played by the protein Cx36, a team of scientists at the University of Geneva have perfected an innovative method which enables testing the effectiveness ...

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