Genetics

Cell-free DNA provides a dynamic window into health

Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers ...

Inflammatory disorders

New imaging agent spotlights inflammation

Many of the most common diseases—cancer, diabetes, cardiovascular and lung disease, and even COVID-19—have been linked to chronic or excessive inflammation. Blood tests can indicate that some part of a person's body is ...

Immunology

New technique can reduce heart transplant rejection

University of Manchester scientists have discovered that removing immune cells from donor hearts using a new technique can reduce the risk of acute rejection after heart transplant surgery—even without the use of powerful ...

Immunology

Immune system discovery could end chronic organ rejection

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled ...

Diabetes

Post-transplant diabetes may be reversible

Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at Vanderbilt ...

Surgery

Looking for clues to improve the life of a transplanted organ

The Transplant Research Program (TxRP) at Boston Children's Hospital is the only pediatric transplantation research program in the U.S committed to better understanding the molecular basis for organ rejection after transplantation ...

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