Immunology

Experts uncover first molecular events of organ rejection

Researchers at the University of Pittsburgh School of Medicine and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ. The ...

Immunology

Immune system discovery could end chronic organ rejection

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled ...

Medical research

Adult stem cells take root in livers and repair damage

Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.

Medical research

Genetically engineered pigs: Advance looks promising

Stories of people waiting for organ transplants that could save their lives are well known. The numbers, though, are not encouraging. The US Department of Health and Human Services has some data: 122,407 people need a lifesaving ...

Medical research

Organ transplant rejection may not be permanent

Rejection of transplanted organs in hosts that were previously tolerant may not be permanent, report scientists from the University of Chicago. Using a mouse model of cardiac transplantation, they found that immune tolerance ...

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