Oncology & Cancer

YBX1 as a key regulator of mitochondrial pyruvate uptake

Cancer metastasis is a crucial area in cancer research that directly affects patient survival and treatment outcomes. Cancer cells often undergo adaptive metabolic changes during metastasis from in situ to distant organs ...

Oncology & Cancer

Transporter protein involved in renal reabsorption of cystine

Cystinuria occurs in one out of every 7,000 in the world, one out of every 10,000 -20,000 in Japan, but its curative treatment has not been established. AGT1/SLC7A13, a protein, is an unknown factor that binds with the protein ...

Medical research

Study: Prazosin inhibits endocytic sorting

In a study just published in Proceedings of the National Academy of Sciences, Dr Ulrike Eggert et al. demonstrated that the drug Prazosin inhibits endocytic sorting.

Oncology & Cancer

Research proposes new way to reverse resistance to chemotherapy

A serious medical problem that oncologists face is multi-drug resistant cancers. In order to address this issue, Guillermo Aquino-Jarquín from the Children's Hospital Federico Gómez of Mexico, seeks expression profiles ...

Medical research

UM brain disorder research moves toward clinical testing

University of Montana is one step closer to turning a discovery into a drug. Promentis Pharmaceuticals, Inc. recently announced it will enter an exclusive agreement with UM to commercialize a discovery made by a team of UM ...

Medical research

Unlocking the therapeutic potential of SLC13 transporters

Researchers have provided the first functional analysis of a member of a family of transporter proteins implicated in diabetes, obesity, and lifespan. The study appears in the June issue of The Journal of General Physiology.

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