In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of ...
Dec 29, 2020
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Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Jülich Research Center, Germany, and uncovered how sodium ions drive glutamate ...
Dec 21, 2020
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Recent estimates indicate a prevalence of autism spectrum disorder (ASD) in the United States of 1 in 59 children with a well-established 4:1 male predominance. Individual costs for care are estimated at about $2.4 million, ...
Sep 2, 2020
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A new study reveals intricate details about the biology of the huntingtin protein (HTT), which is responsible for Huntington's disease.
Jul 17, 2020
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In biology, it is well-known that every living organism is triggered by the DNA that encodes various protein molecules, which in turn perform all the necessary biological functions, and it might seem that nothing else is ...
May 27, 2020
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A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice. These mice then showed severe alterations of specific behaviors that closely resemble those seen in human ...
Jul 24, 2019
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For the first time, Bernese researchers have been able to solve the structure of a transport protein and thus to describe the functional mechanism that plays a significant role in the survival of cancer cells. This is an ...
Jun 20, 2019
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Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucléaires de Bordeaux Gradignan (CNRS/Université de Bordeaux) have demonstrated the consequences of a mutation responsible for ...
Jan 16, 2019
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To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.
Aug 23, 2018
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Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study, ...
Aug 7, 2017
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