(HealthDay)—Models based on machine learning and optimization could improve chemotherapy regimens to be tested in phase III clinical trials without altering the toxicity outcomes, according to a study published in the May ...
May 9, 2016
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Each week in the United States, about 300 children are diagnosed with cancer. Many of them will be offered treatment as part of a clinical trial that tests different drugs or different ways to give standard drugs.
Feb 25, 2016
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Lupuzor may become the first specific and non-immunosuppressant therapy for lupus, a disabling autoimmune disease that is currently incurable. Discovered by Sylviane Muller's team in the CNRS Immunopathologie et Chimie Thérapeutique ...
Dec 15, 2015
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University of South Florida Distinguished Professor Benjamin Djulbegovic, MD, PhD, has studied the ethics of randomized clinical trials and their effectiveness in evaluating the outcomes of new treatments for decades.
Aug 27, 2013
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Generally, FDA-approved clinical trials progress through three phases: the first shows safety, the second starts to explore effects and the third seeks to prove a drug's superiority over existing treatments. But when a drug's ...
Aug 8, 2013
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(HealthDay)—Although the U.S. Food and Drug Administration Amendments Act requires publication of the results of completed trials of cancer drugs conducted in the United States, results for almost half of the studies have ...
Jul 23, 2013
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(Medical Xpress)—McGill University post-doctoral fellow Spencer Phillips Hey and Prof. Jonathan Kimmelman, Biomedical Ethics, Social Studies of Medicine, Faculty of Medicine argue that some clinical trials of new drugs ...
May 9, 2013
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If Don Stein were the kind of man who listened to what others said, he would have shut down his lab years ago. The Emory neuroscientist spent more than two decades investigating progesterone as a treatment for traumatic brain ...
Apr 24, 2013
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A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month ...
Jan 24, 2013
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Spin and bias exist in a high proportion of published studies of the outcomes and adverse side-effects of phase III clinical trials of breast cancer treatments, according to new research published in the cancer journal Annals ...
Jan 9, 2013
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