Immunology

Monocytes have many faces

When the immune system mobilizes its troops, antigen-presenting cells play an important role. They emerge from white blood cells (monocytes) that circulate in the blood. An international research team under the leadership ...

Oncology & Cancer

'Double decker' antibody technology fights cancer

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have created a new class of antibody-drug conjugates (ADCs), using a versatile "double decker" technology that ties antibodies and a drug together ...

Medical research

The molecular underpinnings of T cell exhaustion

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can ...

Oncology & Cancer

Dual antigen targeting may improve CAR T cell cancer therapy

A solid tumor comprises a heterogeneous population of cells that differ from each other on their type of surface molecules. In an article published today in the Journal of Clinical Investigation, researchers from Baylor College ...

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