Medical research

The molecular underpinnings of T cell exhaustion

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can ...

Oncology & Cancer

Dual antigen targeting may improve CAR T cell cancer therapy

A solid tumor comprises a heterogeneous population of cells that differ from each other on their type of surface molecules. In an article published today in the Journal of Clinical Investigation, researchers from Baylor College ...

Oncology & Cancer

Tests to gauge genetic risks for prostate cancer now are feasible

Men with an elevated, genetically inherited risk for prostate cancer could be routinely identified with a simple blood or urine test, scientists at UC San Francisco and Kaiser Permanente Northern California have concluded, ...

Oncology & Cancer

New test to predict the effectiveness of cancer vaccines

Cancer vaccines are designed to turn the body's own immune system specifically against tumor cells. Particularly promising are vaccines that are directed against so-called neoantigens: These are proteins that have undergone ...

page 9 from 12