Researchers at The University of Texas MD Anderson Cancer Center have discovered that two distinct classes of cancer-associated fibroblasts (CAFs) accumulate in the pancreatic tumor microenvironment and play opposing roles ...
Mar 29, 2022
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Stimulating the body's immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies to achieve that: taking off the brakes that tumors put on the immune system; ...
Jan 11, 2022
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Analysis of data from the I-SPY 2 clinical trial showed that race did not significantly affect several key measures of breast cancer treatment outcomes, including pathologic complete response and event-free survival, according ...
Dec 8, 2021
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In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach. It is based on using humanized antibodies called immune checkpoint inhibitors (ICIs) to block the cellular pathways ...
Dec 7, 2021
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Apoptosis is the mechanism by which defective cells promote their own death to protect the body. It is a complex process, with many stages, in which the different parts of the cell gradually degrade. In glioblastoma cells, ...
Nov 23, 2021
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Researchers have identified a molecular mechanism that drives the progression of uveal melanoma (UM), an often lethal eye cancer in adults.
Sep 13, 2021
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A new paper soon to be released in the Journal of the National Cancer Institute indicates that early-onset colorectal cancer is likely not a different disease from average-onset colorectal cancer.
Aug 18, 2021
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Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal ...
Jul 23, 2021
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Neoadjuvant immune checkpoint blockade (ICB) is a promising treatment for melanoma and other cancer types, and has recently been shown to provide a modest survival benefit for patients with recurrent glioblastoma. To improve ...
Jun 29, 2021
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Researchers from Karolinska Institutet have discovered how platinum chemotherapy can enhance the treatment resistance of ovarian cancer cells, by progressively changing the cancer cell-intrinsic adhesion signaling and cell-surrounding ...
Jun 24, 2021
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