Immunology

Researchers show how cancer cells may respond to mechanical force

The push and pull of physical force can cause profound changes in the behavior of a cell. Two studies from researchers working at the UNC Lineberger Comprehensive Cancer Center reveal how cells respond to mechanical manipulation, ...

Oncology & Cancer

Targeted treatment for ovarian cancer discovered

Researchers at Women & Infants Hospital of Rhode Island have developed a biologic drug that would prevent the production of a protein known to allow ovarian cancer cells to grow aggressively while being resistant to chemotherapy. ...

Oncology & Cancer

Prostate cancer biomarker may predict patient outcomes

Researchers at Vanderbilt University Medical Center and the University of Alberta in Canada have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their ...

Oncology & Cancer

Predicting cancer's next move

Research led by Broad senior associate member Levi Garraway and published this week in Nature offers a new approach to studying drug resistance in cancer. The approach helped them identify which biological pathways could ...

Oncology & Cancer

Blood-pressure drug may help improve cancer treatment

Use of existing, well-established hypertension drugs could improve the outcome of cancer chemotherapy by opening up collapsed blood vessels in solid tumors. In their report in the online journal Nature Communications, Massachusetts ...

Oncology & Cancer

Watching tumors burst through a blood vessel

Cancer cells metastasize in several stages—first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually ...

Oncology & Cancer

'Wildly heterogeneous genes'

Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments.

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