Reactive oxygen species (ROS) can act as signal carriers during the evolution of malignant tumors. At the appropriate concentration, ROS mediate signal transduction and cell growth. However, ROS are a double-edged sword, ...
Oct 20, 2021
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A Ludwig Cancer Research study has identified and preclinically validated combination treatments for the brain metastases of breast cancer, a common and typically lethal manifestation of the malignancy. The combination therapy, ...
Oct 18, 2021
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A team of researchers working at the Indiana University School of Medicine, has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, ...
While substantial strides have been made against some types of childhood cancers, high-grade gliomas still lack effective treatments.
Oct 13, 2021
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The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune ...
Oct 12, 2021
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A peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint inhibitors in preclinical cancer models, according to results presented at the AACR-NCI-EORTC Virtual ...
Oct 7, 2021
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Growing blood vessels are experts at multitasking. Not only do cells in their walls divide, they must also sprout in new directions while learning to specialize, ultimately becoming part of vein, artery or lymphatic vessels. ...
Oct 5, 2021
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A team of researchers at the Translational Health Science and Technology Institute has found evidence that suggests adding salt to the mouse diet can suppress the growth of cancerous tumors. In their paper published in the ...
Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.
Sep 16, 2021
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Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs. The treatment not only slowed ...
Sep 14, 2021
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