Genetics

Early genetic development of the brain mapped

In an article published in Nature, researchers from Karolinska Institutet present an atlas of the early development of the brain. The atlas can be used, among other things, to find out what went wrong in the development of ...

Oncology & Cancer

Potential therapeutic target for small cell lung cancer discovered

Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer (SCLC) cells may decrease cancer cell differentiation and tumor ...

Transforming growth factor

Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.

The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.

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