(Medical Xpress)—One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body. In order to investigate ...
Oct 18, 2013
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Biologists at The Johns Hopkins University have discovered that low oxygen conditions, which often persist inside tumors, are sufficient to initiate a molecular chain of events that transforms breast cancer cells from being ...
Dec 26, 2013
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Approximately 15-to-30 percent of patients with metastatic breast cancer have brain metastasis (BM), with basal-like breast cancer (BLBC) metastasizing to the brain most frequently. The prognosis for BLBC-BM patients is poor, ...
Mar 5, 2021
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A new study reveals key factors that promote the spread of cancer to lymph nodes and provides a mechanism that explains how a common over-the-counter anti-inflammatory medication can reduce the spread of tumor cells through ...
Feb 13, 2012
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Researchers from the Harper Cancer Research Institute, a partnership between the University of Notre Dame and Indiana University School of Medicine-South Bend, have uncovered a key element that plays a role in the spread ...
Nov 7, 2011
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Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease. This makes inhibition of the ALK1 pathway a possible ...
Jun 15, 2015
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The Liquid Biopsy and Cancer Interception research group—part of the Biohealth Research Institute in Granada (ibs.GRANADA), in which researchers from the University of Granada (UGR) participate—has discovered that tumor ...
Mar 30, 2022
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In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.
Aug 31, 2022
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A new study finds that a group of little-explored cells in the tumor microenvironment likely serve as important gatekeepers against cancer progression and metastasis. Published in the January 17 issue of Cancer Cell, these ...
Jan 17, 2012
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An international clinical trial has found that treatment with a drug that suppresses the normal breakdown of bone can delay the development of bone metastases in men with prostate cancer. The study, receiving Online First ...
Nov 16, 2011
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