The development of various hypoxia-activated prodrugs (HAPs) has made considerable advances in the last few decades; however, cancer therapy using HAPs is still hindered by problems such as poor therapeutic outcomes due to ...
Apr 4, 2023
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Cancer cells have developed multiple mechanisms to thrive. One example, derived from age-old theories of evolution, is positive selection i.e., the propensity of cells with favorable cancer mutations to flourish. However, ...
Jan 18, 2023
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Radiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radiotherapy still suffers from shortcomings such as serious side effects, limited efficacy, and tumor metastasis and recurrence due ...
Jan 10, 2023
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A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.
Jul 25, 2022
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Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma. Although new immunotherapies are effective in some patients with melanoma brain metastases, ...
Jul 16, 2022
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Research led by investigators at Cedars-Sinai Cancer and Johns Hopkins University have discovered a novel three-step treatment that disrupts the pancreatic tumor microenvironment in laboratory mice.
Jul 11, 2022
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Progress towards a unique vaccine targeting specific breast cancer antigens has been shown to delay tumor growth and prevent breast cancer metastasis in preclinical models in a study led by the Malaghan Institute of Medical ...
Jul 5, 2022
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The Liquid Biopsy and Cancer Interception research group—part of the Biohealth Research Institute in Granada (ibs.GRANADA), in which researchers from the University of Granada (UGR) participate—has discovered that tumor ...
Mar 30, 2022
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Chemotherapy is known for its painful side-effects. It also has limitations when the cancer has metastasized to the lymph nodes. The lymphatic drug delivery system, where anticancer drugs are injected directly into the sentinel ...
Mar 29, 2022
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An article recently published in The Journal of Clinical Investigation by the group of Dr. Maria Caffarel and Miguel Servet shows for the first time that the proinflammatory cytokine Oncostatin M (OSM) favors breast cancer ...
Mar 24, 2022
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