New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK), and published today in the journal Cell, support an emerging framework in cancer science that views metastasis as not primarily driven by genetic ...
Feb 3, 2022
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Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows.
Sep 23, 2021
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Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.
Apr 20, 2021
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Breast cancer is the most frequent neoplasm among women, impacting 2.1 million women per year. It also has a high risk for intracranial spread. Researchers estimate that up to 30% of all patients with cancer will eventually ...
Sep 28, 2020
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The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer ...
Mar 19, 2020
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A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis.
Feb 5, 2020
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Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To undergo metastasis, cells must leave the primary tumor, invade the microenvironment, circulate ...
Nov 5, 2019
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While researchers have a basic understanding of how primary cancer cells grow, less is known about metastasis, the deadly process by which cancers spread. A team led by Dr. Paul Krebsbach, dean of UCLA's School of Dentistry ...
Jul 11, 2019
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Head and neck tumors that contain cells undergoing a partial epithelial-to-mesenchymal transition—which transforms them from neatly organized blocks into irregular structures that extrude into the surrounding environment—are ...
Nov 30, 2017
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Hasini Jayatilaka was a sophomore at the Johns Hopkins University working in a lab studying cancer cells when she noticed that when the cells become too densely packed, some would break off and start spreading.
Jun 20, 2017
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