While the importance of the triggering receptor expressed on myeloid cells 2 (TREM2) is known in brain microglial function during neurodegenerative diseases, the function of the TREM2 cell receptor/protein is unknown in glioblastoma ...
Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible ...
May 17, 2023
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Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11%. Two separate labs at Boston Children's Hospital took out-of-the-box ...
Apr 25, 2023
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A team has revealed the key mechanism of the loss of membrane protrusions on intratumoral natural killer (NK) cells, which impairs their ability to recognize and kill tumor cells, providing a new strategy for NK cell-based ...
Apr 10, 2023
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In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer. But despite significant advances, there is still a lack ...
Mar 29, 2023
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Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative ...
Mar 28, 2023
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Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targeting a different type of immune cell called macrophages could be a more effective approach, ...
Mar 16, 2023
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When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half or more of all human white blood cells.
Mar 9, 2023
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A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.
Feb 28, 2023
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Platinum-based chemotherapy, which is used to treat advanced colorectal cancer, accumulates in the healthy cells surrounding the cancer cells and, as a result, can reduce tumor sensitivity to treatment. This is demonstrated ...
Feb 24, 2023
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