Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious ...
May 18, 2020
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In its first clinical trial in patients with a hard-to-treat form of uterine cancer, a targeted drug that subjects tumor cells to staggering levels of DNA damage caused tumors to shrink in nearly one-third of patients, investigators ...
Apr 24, 2020
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Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.
Apr 21, 2020
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A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors.
Apr 14, 2020
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A team of researchers affiliated with several institutions in Canada has identified 15 tumor suppressor genes that can trigger rapid growth of human head and neck squamous cell carcinoma (HNSCC) when they mutate. In their ...
Tracking brain cancer with a blood test instead of a surgical biopsy may greatly improve quality of life for glioblastoma (GBM) patients and provide critical information for their care, but it is not feasible in all cases. ...
Feb 27, 2020
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A massive analysis of the entire genomes of 2,658 people with 38 different types of cancer has identified mutations in 179 genes and gene regulators as "drivers"—variations in DNA sequences that lead to the development ...
Feb 20, 2020
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Scientists from the German Cancer Research Center systematically investigated the DNA of more than 2,600 tumor samples from patients with 38 types of cancer to discover traces of viruses, which they found in 13 percent of ...
Feb 5, 2020
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T cells targeting p53 hotspot mutations can be harvested from peripheral blood of patients with metastatic solid epithelial cancers, according to results published in Clinical Cancer Research, a journal of the American Association ...
Jan 29, 2020
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A new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) shows how resistance to a promising targeted ...
Jan 14, 2020
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