Genetics

Gene in eye melanomas linked to good prognosis

Melanomas that develop in the eye often are fatal. Now, scientists at Washington University School of Medicine in St. Louis report they have identified a mutated gene in melanoma tumors of the eye that appears to predict ...

Oncology & Cancer

Mechanism for invasion of tumorous cells discovered

Researchers at the Hebrew University of Jerusalem have discovered a previously unknown mechanism whereby tumor cells invade normal tissues, spreading cancer through various organs.

Oncology & Cancer

Epilepsy drug stops nervous system tumor growth in mice

People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign—meaning they don't spread to other parts of the body and are not considered life-threatening—but ...

Oncology & Cancer

DGK-alpha helps cancer cells gain traction and mobilize

Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.

Oncology & Cancer

Gene-editing technique could speed up study of cancer mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how they contribute to cancer because there's ...

Oncology & Cancer

A new way to model cancer

Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw—but breeding such ...

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