Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network ...
Sep 11, 2014
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Cancer therapies targeting specific genetic mutations may offer benefits to patients for whom other standard chemotherapy treatments have not effectively treated their tumor. However, genetic screening of tumors is not routinely ...
Apr 5, 2022
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Researchers from the UNC Lineberger Comprehensive Cancer Center analyzed hundreds of melanoma samples to find out if two genetic mutations more commonly found in melanoma tumors were associated with lower survival rates in ...
Apr 13, 2015
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Meningiomas, a type of brain tumour, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and have high recurrence rates, i.e. there is a high risk of them coming back after treatment. ...
Nov 19, 2018
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The Food and Drug Administration expanded approval of a Pfizer drug to treat a small subset of lung cancer patients with a rare mutation.
Mar 11, 2016
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An international team of researchers has established the cause of rare syndrome consistent with Fanconi Anemia: a de novo mutation in a so called RAD51 gene, which is responsible for repairing damages in the DNA. Fanconi ...
Dec 22, 2015
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Cancer is often seen as a disease that arises from genetic mutations causing cells to divide uncontrollably and invade other parts of the body. But the spread of cells away from their origins is actually a normal process ...
Feb 10, 2023
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Certain mutations of the gene ATRX were associated with age at diagnosis in children and young adults with advanced-stage neuroblastoma, a cancer that grows in parts of the nervous system, according to a study in the March ...
Mar 13, 2012
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A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits such as uncontrolled ...
Feb 4, 2013
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Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse. The research, published in Cancer Cell, could translate into improved patient care strategies ...
Mar 6, 2014
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