Oncology & Cancer

Mysterious gene transcripts after cancer therapy

Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...

Oncology & Cancer

Combination therapy targets genetic mutation found in many cancers

A study at The University of Texas MD Anderson Cancer Center has shown promise for effective treatment of therapy-resistant cancers caused by a mutation of the RAS gene found in many cancers. The pre-clinical study combined ...

Oncology & Cancer

Better treatment for kidney cancer thanks to new mouse model

Research in the field of kidney cancer, also called renal cancer, is vital, because many patients with this disease still cannot be cured today. Researchers from the University of Zurich have now identified some of the gene ...

Oncology & Cancer

New model could speed up colon cancer research

Using the gene-editing system known as CRISPR, MIT researchers have shown in mice that they can generate colon tumors that very closely resemble human tumors. This advance should help scientists learn more about how the disease ...

Genetics

Solving the mystery of meningiomas reveals a surprise twist

In solving one mystery—the genetic roots of benign brain tumors called meningiomas—a team of scientists led by Yale researchers stumbled upon an even greater one: How is it possible that two of the mutations linked to ...

Oncology & Cancer

Taking aim at rare cancer variants

If you walked into a cancer clinic ten years ago as a newly diagnosed patient, you'd likely get "standard of care" treatment based on the location of the cancer in your body and its stage. Make that same visit today and your ...

Genetics

Study sheds light on role of mutations in metastasized cancer

Approximately 95 percent of cancer mortality is caused by metastasis. This fact is what motivates many cancer researchers to focus on finding new ways to stop or kill the growth of metastatic cancer cells. A new paper published ...

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