The tumor microenvironment (TME) is a mix of fluids, immune cells and blood vessels which envelops the tumors. Interactions between tumor cells and the TME determine the progression and fate of tumors. Therefore, understanding ...
Jul 8, 2019
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Researchers from the Hubrecht Institute and Radboud University have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Using this ...
May 23, 2019
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A new Northwestern Medicine study finds that a combination of two mutations cause a form of pediatric brain tumors to become more deadly, according to findings published in Nature Communications.
May 16, 2019
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A tumor can contain remarkable diversity, where even neighboring cells may differ greatly in terms of the mutations they contain. A device that can overcome this heterogeneity by enabling efficient analysis of both DNA and ...
Apr 30, 2019
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Melanomas tend to be "hot" or "cold—if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, ...
Apr 3, 2019
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Vaccination with as few as four tumor antigens generated antigen-specific responses, reduced intestinal tumors, and improved survival in a mouse model of Lynch syndrome, suggesting that it may be possible to develop a cancer ...
Apr 1, 2019
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A few months ago, Lisa Diller saw a family for a consultation in her cancer clinic. Their story is one of tragedy, and of hope.
Apr 1, 2019
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Cancer, in all its forms, seems to always involve uncontrolled cell growth; but there are thousands of ways in which cells can lose control of their proliferation in the first place. Among a huge variety of proteins known ...
Mar 22, 2019
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Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina ...
Mar 19, 2019
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A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma (DIPG) - the most deadly brain ...
Mar 4, 2019
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