Neuroscience

New impetus for treatment neurodegenerative diseases

Twenty years ago, tumor necrosis factor (TNF) seemed a promising target in the treatment of brain diseases like multiple sclerosis or Alzheimer's Disease. But clinical trials produced disappointing results. Now University ...

Neuroscience

Mechanism that reduces effect of cocaine on brain discovered

A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre (RI-MUHC) in ...

Immunology

Immune factor allows viral infections to become chronic

Many viral diseases tend to become chronic - including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently. Scientists at the University of Bonn have ...

Oncology & Cancer

Nutrient deprivation kills kidney cancer cells

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread.

Oncology & Cancer

Cancer-killing proteins destroy tumor cells in bloodstream

Cornell researchers have discovered potent cancer-killing proteins that can travel by white blood cells to kill tumors in the bloodstream of mice with metastatic prostate cancer. The breakthrough study will be published Feb. ...

Cardiology

Prognostic biomarkers ID'd in pulmonary hypertension

(HealthDay)—Biomarkers have been identified for the risk of lung transplantation and death in patients with pulmonary arterial hypertension (PAH), according to a study published online Oct. 26 in the Annals of the American ...

Diseases, Conditions, Syndromes

Serotonin levels low in ankylosing spondylitis

(HealthDay)—Patients with ankylosing spondylitis (AS) have lower serotonin levels than healthy controls and patients with rheumatoid arthritis (RA), according to a study published online Sept. 30 in the Journal of Bone ...

Diseases, Conditions, Syndromes

Tumor necrosis factor in colitis—bad actor or hero?

Investigators at Children's Hospital Los Angeles have found that a common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation by inhibiting pathogenic ...

page 9 from 18