The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of ...
Jan 12, 2018
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Lung cancer is the leading cause of cancer-associated deaths. One of the most promising ways to treat it is by immunotherapy, a strategy that turns the patient's immune system against the tumor. In the past twenty years, ...
Dec 12, 2017
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Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, ...
Dec 12, 2017
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When researchers at the University of São Paulo (USP) in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric (Curcuma longa) its orange color, they ...
Dec 7, 2017
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Massachusetts General Hospital (MGH) investigators have identified a way in which a type of lung cancer co-opts a portion of the immune system to increase tumor progression. In the Dec. 1 issue of Science, the team from the ...
Nov 30, 2017
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Researchers from Harvard Medical School and the Institute of Systems Biology have discovered that the remains of tumor cells killed by chemotherapy or other cancer treatments can actually stimulate tumor growth by inducing ...
Nov 30, 2017
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Researchers from The Wistar Institute discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an immunotherapeutic strategy that inhibits ...
Nov 13, 2017
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Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego have shown that tumors can ensure a more reliable nutrient supply by eliminating the p62 protein in surrounding stromal tissue. Specifically, ...
Oct 6, 2017
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(HealthDay)—For patients with locally advanced or metastatic pancreatic carcinoma with malignant ascites, a combined systemic and intraperitoneal chemotherapy approach plus hyperthermia is well tolerated and active, according ...
Jul 31, 2017
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Liver cancer tumors are genetically diverse and therefore difficult to treat, a Singaporean research team reports. The genetic differences found in each patient may one day enable personal, targeted therapies to treat the ...
Jun 28, 2017
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