Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly. The results highlight a potential new strategy for developing targeted treatments ...
Jan 17, 2024
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The p53 tumor suppressor protein is encoded by TP53, the most frequently mutated gene in cancer. A review article published in Nature Reviews Clinical Oncology by Professor Klas G Wiman and colleagues at the Department of ...
Dec 19, 2023
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A study by researchers at Columbia and the Hong Kong University of Science and Technology is helping to clarify how low-grade lymphoma changes as it develops into a more aggressive tumor, which could lead to the development ...
Dec 18, 2023
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A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells. These effects dampen the capacity ...
Dec 15, 2023
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Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death. A study led by the Protein Kinases ...
Dec 14, 2023
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Cancer metastasis is a crucial area in cancer research that directly affects patient survival and treatment outcomes. Cancer cells often undergo adaptive metabolic changes during metastasis from in situ to distant organs ...
Dec 6, 2023
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The p53 protein is a tumor suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective in cells, the protein can significantly boost a person's risk of cancer ...
Nov 28, 2023
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A review paper titled "Targeting Ras with protein engineering" has been published in Oncotarget.
Nov 27, 2023
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A new study by Tulane University has uncovered a previously unknown molecular pathway that could be instrumental to halting lung cancer in its tracks.
Nov 27, 2023
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MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins—with clear consequences for the tumor.
Nov 7, 2023
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