Deletion of the HIRA protein promotes the proliferation and invasion of tumor cells in cell culture and animal models. That is the result of a research endeavor led by Alexander von Humboldt Professor Dr. Christian Frezza ...
Oct 26, 2022
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Investigators have designed an antibody-based treatment that eliminated circulating tumor cells (CTCs) in mouse models of breast and pancreatic cancer. The research, which was led by scientists at Massachusetts General Hospital ...
Oct 20, 2022
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During brain development, neurons have to migrate long distances through complex environments until they reach their final destination. In order to find guidance, they must establish several interactions—which are still ...
Oct 18, 2022
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About one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them resistant to endocrine therapy and able to grow uncontrolled. A team of researchers at Baylor College of ...
Oct 17, 2022
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Targeted therapies specifically attach to and hinder cancer-causing proteins, but cancer cells can quickly evolve to thwart their action. A second drug class, immunotherapies, harnesses the immune system to attack cancer ...
Oct 17, 2022
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This year, about 240,000 people in the U.S. will discover they have lung cancer. Some 200,000 of them will be diagnosed with non-small-cell lung cancer, which is the second leading cause of death after cardiovascular disease.
Oct 6, 2022
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A deep dive into the proteins and protein activities of human tumors grown in mouse models expands the potential therapeutic pathways to treat medulloblastoma, according to a new study published in the Journal of Proteome ...
Sep 27, 2022
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A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms by which the p53 protein, often called the guardian of the genome, regulates gene expression by looking for novel proteins that interact with the versatile ...
Sep 20, 2022
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Researchers at the University of Gothenburg have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice. This discovery may potentially enable future development of new drugs against ...
Aug 30, 2022
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A study conducted by researchers in Brazil, Australia, Austria and the United States has made significant discoveries about a type of pediatric cancer with no approved drugs for treatment and with a low survival rate. The ...
Aug 29, 2022
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