Proteins and other therapeutic compounds injected directly into the blood stream tend to be broken down rapidly by the immune system. Now, researchers in Singapore have demonstrated in mice that the anticancer protein, interferon-α2a ...
Jul 3, 2013
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Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...
Nov 5, 2012
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Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine (IRB Barcelona) led a study in which they designed a new strategy to get genetically modified viruses to selectively ...
Mar 16, 2017
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The tumor suppressor protein called adenomatous polyposis coli (APC) is a central genetic risk factor for colorectal cancer. In fact, mutations that potentially alter the structure or function of this protein are found in ...
Feb 17, 2012
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The process of cell division is tightly regulated, as mistakes may lead to cancer. The so-called c-JUN protein has been fingered as causing tumors in both skin and liver. The group of Veronika Sexl at the University of Veterinary ...
Jun 28, 2011
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Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body ...
Dec 15, 2014
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Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, scientists don't ...
Apr 10, 2023
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Proteins that are frequently altered in tumors play a prominent role in cancer research. The protein RFX7, a largely unknown transcription factor, has recently been linked to lymph node cancer. Researchers at the Leibniz ...
Jul 19, 2022
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Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply can be fatal ...
Apr 15, 2013
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Tumor growth is dependent on interactions between cancer cells and adjacent normal tissue, or stroma. Stromal cells can stimulate the growth of tumor cells; however it is unclear if tumor cells can influence the stroma.
Sep 4, 2012
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