Oncology & Cancer

Probing the mechanism of ADAM28-mediated cancer metastasis

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...

Oncology & Cancer

Study sheds light on how cancer spreads in blood

A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these ...

Oncology & Cancer

From genomic data to new cancer drug

New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell demonstrates how genetic insights ...

Inflammatory disorders

IL-32 expression upregulated in chronic rhinosinusitis

(HealthDay) -- Interleukin-32 (IL-32) mRNA expression is significantly higher in biopsies obtained from patients with chronic rhinosinusitis (CRS), compared to levels found in biopsies obtained from individuals without the ...

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