Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year. Cumulative exposure to ultraviolet light is the primary environmental ...
Mar 30, 2020
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While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another ...
May 28, 2013
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One of the hopes for victory against cancer hinges on naturally-occurring proteins whose job is to make their host cell die.
Feb 3, 2014
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Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study. Published ...
Aug 12, 2013
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The formation of tumors in the eye can cause blindness. But, for some reason our corneas, the transparent layer that forms the front of our eyes, have a natural ability to prevent it.
May 11, 2017
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have led a study published in PLoS One showing that the inhibition of a family member of NADPH oxidase enzyme, NOX4, plays an important role in liver fibrosis.
Nov 5, 2012
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Researchers at Oregon State University have discovered a genetic function that helps one of the most important "tumor suppressor" genes to do its job and prevent cancer.
Feb 3, 2014
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(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth in check. The ...
Feb 13, 2013
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The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...
Jan 16, 2013
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A review paper titled "Targeting Ras with protein engineering" has been published in Oncotarget.
Nov 27, 2023
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